BORS was pleased to contribute two well-attended symposia at the European Orthopaedic Research Society (EORS) 2025 meeting, showcasing the strength and breadth of UK musculoskeletal research. Both sessions featured current and former members of the BORS Executive and highlighted cross-institutional collaboration.

Diabetic Bone – New Approaches to the Understanding of the Role of Neuropathy on Bone, Joint Integrity and Repair

Led by Ms Ines Reichert, this session brought together clinical and computational perspectives on how diabetes and peripheral neuropathy impact bone and joint health. Ines discussed multidisciplinary treatment strategies for Charcot neuroarthropathy, drawing on extensive clinical experience. Dr Andrew Phillips presented advanced modelling of bone adaptation in diabetes, highlighting the role of impaired mechanoregulation. Dr Tony Herbert shared biomechanical testing results from diabetic bone and introduced decellularised bone scaffolds as a future platform for in-vitro disease modelling.

Modelling OA: What’s New?

Co-led by Professor Karina Wright and Dr Tim Hopkins, this symposium explored current innovations in osteoarthritis modelling, from cellular mechanisms to advanced simulations.

Professor Debbie Mason presented work on identifying mechanical drivers of osteoarthritis using osteocyte models and patient synovial fluid. Her research links joint loading with early molecular changes in bone remodelling and inflammation. Dr Tim Hopkins, one of this year’s BORS–BJR Travelling Fellows, introduced novel organ-on-a-chip models that mimic cartilage–synovium crosstalk, enabling patient-specific insights into OA pathogenesis. Professor Andrew McCaskie highlighted the role of machine learning in stratifying patients for early intervention and improving clinical trial design. Professor Richie Gill discussed fluid–structure interaction models of cancellous bone, offering new perspectives on how internal bone pressures may relate to OA pain.

Looking Ahead

BORS was pleased to engage with the EORS Executive during the meeting and looks forward to building future collaborations. The strong presence of UK-based research at EORS 2025 reflects our ongoing commitment to advancing orthopaedic science through partnership and innovation.