British Orthopaedic Research Society

The British Orthopaedic Research Society (BORS) is a multidisciplinary association devoted to facilitating collaboration in orthopaedic and musculoskeletal research.


Monday 13 September

09:00Day 1 Opens
09:00 to 09:10Welcome to BORS 2021
BORS President: Deborah Mason
09:10Session 1 | Hips 1
Chairs: Salma Chaudhury (Oxford) and Wasim Khan (Cambridge)
09:10 to 09:40Keynote
Navigating the Cam: Collaboration is the key!
Vikas Khanduja (Cambridge)
09:40 to 10:10Podium Presentations

09.40 Biomechanics of cam-type femoroacetabular impingement: A systematic review
Sunil Kumar (87)
09.47 Development of a geometric characterisation methodology for the assessment of dual mobility liners used in total hip replacement
Brown (18)
09.54 Development of a system for tracking liner orientation in dual mobility hip replacements
Shuttleworth (17)
10.01 The effect of sarcopenia on outcomes following orthopaedic surgery: A systematic review
Brzeszczyński (19)
10:10 to 10:30Break and Posters | Hips

Does the type of sport influence morphology of the hip? A systematic review
Sunil Kumar (84)
A randomised controlled trial comparing multiplayer and single player immersive virtual reality training for anterior approach total hip arthroplasty surgery
Edwards (95)
How does the cam morphology develop in athletes? A systematic review and meta-analysis
Sunil Kumar (85)
10:30 Session 2 | Hips 2
Chairs: Chris Bretherton (Oxford) and Richie Gill (Bath)
10:30 to 11:40Podium Presentations

10.35 Effect of stem fixation, stem malalignment, and bone quality in total hip arthroplasty: A finite element study
Wang (35)
10.42 Do patients with well-functioning total hip arthroplasty achieve normal sagittal plane hip kinematics during walking gait? A proof of concept study
Langley (21)
10.49 A randomised controlled trial of spaced practice versus massed training in immersive virtual reality hip arthroplasty simulation
Edwards (91)
10.56 Probabilistic neural network estimation of postoperative PROMs after hip and knee replacement surgeries
de Mello (77)

11.03 Mid-Session Remarks

11.08 Bilateral hip resurfacing arthroplasty restores gait function at increasing walking speeds
Maslivec (54)
11.15 Outcomes following surgical management of femoroacetabular Impingement: A systematic review and meta-analysis of different surgical techniques
Sunil Kumar (79)
11.22 Direct 3D printing of polyetheretherketone/hydroxyapatite composite materials for orthopaedic applications
Boyd (23)
11.29 Biomimetic highly lubricious polyelectrolyte functionalised PEEK surfaces for novel hemiarthroplasty implants and focal resurfacing
Elkington (34)
11:40 to 12:00Break and Posters | Shoulder Arthroplasty

Relationship between preoperative diagnosis and clinical outcomes in reverse shoulder arthroplasty. An experience in 78 shoulders
Mehta (50)
Implant survival and complications following VAIOS® reverse total shoulder replacement
Giles (71)
Dual platform 4th generation shoulder replacement system-medium term results
Komperla (72)
12:00 to 12:40BHS/BORS Network Presentations and Discussion
Chairs: Sophie Williams (Leeds) and Tim Board (Wrightington)
12:40 to 13:30Lunch and Posters | Optimising Surgical Practice

Use of topical tranexamic acid to reduce blood loss in thoracolumbar spine tuberculosis surgery
Kakadiya (33)

Clinical and radiological outcomes of the severe osteoporotic vertebral compression fractures treated with vertebroplasty and short segment cement augmented screw fixation
Kakadiya (10)
Does endoscopy affect recurrence rate when used in curettage of benign osteolytic lesions?
Ahmed Fathy (15)

What is the functional mobility and quality of life in patients with cerebral palsy following single-event multilevel surgery?
Edwards (49)
What are the methods used to present and minimise loss-to-follow-up in studies based on arthroscopy registries?
Sunil Kumar (81)
13:30 to 14:00President’s Medal Keynote
Reflections on BORS
Brigitte Scammell (Nottingham)
14:00Session 3 | Clinical Research
Chairs: Hamish Simpson (Edinburgh) and Muhamed Alanie (Warwick)
14:00 to 14:40Podium Presentations

14.05 Is postoperative non-weight-bearing necessary? (INWN) a pragmatic randomised multicentre trial of operatively treated ankle fracture
Khojaly (94)
14.12 Longer-term risks and benefits of recurrent intra-articular corticosteroid injections for osteoarthritis: a systematic review and meta-analysis
Donovan (27)
14.19 Prolonged operative time associated with increased healthcare utilization after open reduction and internal fixation of intra-articular and extra-articular distal radial fractures: An analysis of 17,482 cases
Emara (1)

14.26 Risk of complications following surgical fixation of femoral diaphyseal fractures in children aged 4 to 12 years: a systematic review and meta-analysis
Daly (26)
14.33 Longer operative time associated with prolonged length of stay, non-home discharge and transfusion requirement after anterior cervical discectomy and fusion: An analysis of 25,107 cases
Emara (2)
14:40 to 15:00Break and Posters | Ankle Trauma

Our management of open and closed Pilon fractures
Lu (90)
Patient-reported outcomes and prognostic factors in ankle fracture-dislocations: A systematic review
Ahmed (63)
Experience of tibiotalocalcaneal fusion using hindfoot nails
Hussain (36)
The use of hindfoot nailing in ankle fractures: a case series
Brachimi (41)
15:00Session 4 | Biomechanics
Chairs: Mark Wilkinson (Sheffield) and Vee San Cheong (Sheffield)
15:00 to 15:40Podium Presentations

15.05 3D Printed medical grade Ti-6Al-4V osteosynthesis devices meet the requirements for tensile strength, bending, fatigue and biocompatibility
MacLeod (69)
15.12 Structural and biomechanical evaluation of decellularised human allograft bone from different anatomical sources
Norbertczak (22)
15.19 Morphometric measurements can improve prediction of progressive vertebral deformity following vertebral damage
Luo (39)
15.26 Modification of decellularisation methods to assess the effects of swelling on the mechanical properties and composition of porcine tendon
Solis (25)
15.33 Complex tibial plateau fractures: A biomechanical investigation
Samsami (12)
15:40Session 5 | Knee
Chairs: Ramy Khojaly (Ireland) and David Hamilton (Edinburgh)
15:40 to 16:40Podium Presentations

15.45 The risk of anterior cruciate ligament (ACL) avulsion fracture with bi-unicondylar knee arthroplasty
Stoddart (76)
15.52 The correlation between an objective classification of gait function pre and post total knee replacement in two cohorts of individuals with knee osteoarthritis
De Vecchis (53)
15.59 Using principal component analysis to identify differences in knee joint function between a non-pathological group and a pre–high tibial osteotomy cohort
Bowd (68)
16.06 Predicting hip-knee-ankle and femorotibial angles from knee radiographs with deep learning
Wang (52)

16.13 Mid-Session Remarks

16.18 Mechanical characterization of bone marrow lesions
Kayode (47)
16.25 A proposed role for tactile joint afferents in pathology
Jones (74)
16.32 Modifying the design of the Oxford domed lateral unicompartmental knee replacement implant reduces the risk of medial bearing dislocation
Yang (20)
16:40 to 17:00Break and Posters | Perioperative Analgesia

Acute pain management following elective orthopaedic shoulder surgery
Salhab (8)

Safety and cost-effectiveness of Inter-scalene Brachial plexus block with sedation in reverse total shoulder replacement
Ramesh (13)
Local infiltration anaesthesia (LIA) is equally effective as adductor canal blocks (ACB) for pain relief in hamstring graft anterior cruciate ligament (ACL) reconstructions
Salhab (9)
17:00 to 17:30Keynote
Engineered functional cartilage models in repair and disease modelling
Adetola Adeside (Alberta)

Chairs: Ines Reichert (KCL) and Matt Seah (Cambridge)
17:30 to 18:30OATech+ Network Presentations and Discussion
Chairs: David Williams (Cardiff) and Rebecca Hamilton (Cardiff)

17:30 Bridging disciplines as a pathway to finding new solutions for osteoarthritis
Tom Andriacchi
18:00 The use of technology within lifestyle interventions in osteoarthritis
Richard Jones
18:15 Do age-related epiphyseal bone differences in osteoarthritic SRT/Ort versus healthy mouse tibias reveal future imaging biomarkers?
Lucinda Evans
18:30Day 1 Close

Tuesday 14 September

09:00Day 2 Opens
09:00Session 6 | Biology
Chairs: Oluwasegun Kayode (Leeds) and Catherine Pendegrass (UCL)
09:00 to 10:10Podium Presentations

09.05 The influence of surrounding matrix environment on the immunomodulatory activity of mesenchymal stromal/stem cells
Alkhrayef (48)
09.12 The use of the transcriptomic signature of mesenchymal stromal cells from various sources to help decide the optimal source for cartilage regeneration
Darlington (93)
09.19 Functional interactions of the long non-coding (lnc) RNA CASC20 in heterotopic ossification
Felix-Ilemhenbhio (65)
09.26 An in vitro system to study the effect of subchondral bone health on articular cartilage repair in humans
Hopkins (38)

09.33 Mid-Session remarks

09.38 Altered acute phase response (APR) signalling following cartilage harvest can be identified in the plasma of ‘non-responder’ patients to autologous chondrocyte implantation
Hulme (11)
09.45 Meta-analysis of adipose tissue derived cell-based therapy for the treatment of knee osteoarthritis
Mak (97)
09.52 The use of bone marrow stem cell derived extracellular vesicles as a therapy for osteoarthritis
Hotham (73)

09.59 What is the evidence from in vivo studies that mesenchymal stem cell derived extracellular vesicles can facilitate tendon and ligament repair?
Lu (86)
10:10 to 10:30Break and Posters | Biology

Measuring nociception in knee OA using physiological and movement responses: A proof-of-concept study
Hamilton (78)
The effect of chronological age on the in vitro properties of infrapatellar fat pad derived mesenchymal stromal cells
Vogt (89)
Glutamate signalling in dogs with cranial cruciate ligament disease
Alves (56)
10:30 to 11:40One Health Session | Part 1
Chairs: Joel Alves (Cardiff) and Chris Little (Sydney)

Introduction to One Health in ACL injury
Eithne Comerford

Expert panel discussion
Panel: Duncan Lascelles, John Innes, Peter Mitchell
11:40 to 12:00Break and Posters | Soft Tissue Injuries

A comparison of arthroscopic simple and complex single-row versus transosseous-equivalent double-row repair techniques for full-thickness rotator cuff injuries; A systematic review and meta-analysis
Raghu (99)
The use of magnetic resonance imaging (MRI) of the knee in current clinical practice: A retrospective evaluation of the MRI reports within a large NHS trust
Moiz (92)
Chronic Achilles rupture management: A scoping review
Lau (6)
12:00 to 12:40One Health Session | Part 2
Moderators: Chris Little (Sydney, Australia) and Deborah Mason (Cardiff)

Expert panel discussion with questions from the audience
12:40 to 13:30Lunch and Posters | Biomechanics

Biomechanical comparisons of bony and tendinous mallet injuries
Giddins (4)
Wrist and hand postures when falling and description of the upper limb falling reflex
Giddins (3)
Over one third of the patients with symptomatic femoroacetabular impingement display femoral or acetabular version abnormalities
Sunil Kumar (80)
Relationship between spinopelvic parameters and symptomatic femoroacetabular impingment: A scoping review
Sunil Kumar (82)
Acetabular erosion in bipolar hemi-arthroplasty for displaced intracapsular neck of femur fracture
McCabe-Robinson (70)
Lack of standardisation in mechanical testing of patella tendon
Sanderson (98)
13:30 to 14:40BORS AGM
14:40 to 15:00Break and Posters | Surgical Implants

3D fabrication of short-stem porous hip implant design for reducing stress shielding and promoting osseointegration
Naghavi (61)
Total and partial knee replacement implants that maintain native load transfer in the tibia
Munford (16)
First clinical experience of a personalised 3D-printed osteotomy system for knee arthritis treatment
MacLeod (67)
15:00Session 7 | In-Silico and In-Vitro Models and Modelling
Chairs: Andrew Phillips (Imperial) and Elise Pegg (Bath)
15:00 to 15:30 Keynote
How in-silico medicine could shape change orthopaedic practice in the future
Damien Lacroix (Sheffield)
15:30 to 16:40Podium Presentations

15.35 Mechanical loading upregulates the piezo1 channel in human stem cell derived osteocytes
Gilbert (51)
15.42 Spatiotemporal effects of mechanical loading and PTH treatments on mouse tibial model of osteoporosis
Cheong (40)
15.49 Validation of a stem cell derived cartilage model for osteoarthritis research and drug screening
Carregosa (62)
15.56 Glutamatergic signalling is regulated by mechanical loading in a 3-dimensional model of human stem cell derived osteocytes
Mason (58)

16.03 Mid-Session Remarks

16.08 Investigating the role of rods and plates in trabecular bone lattices
Phillips (55)
16.15 Development of a finite element model of ankle injury and stability
Hao Chen (37)
16.22 Direct ink writing of polycaprolactone/Laponite composite for bone implants: 3D characterisation using X-ray micro-computed tomography
Chen (75)
16.29 Computational modelling of the control system of a multi-axis spine simulator
Hayward (24)
16:40 to 17:00Break and Posters | Surgical Guidelines

Time to revisit ‘absolute’ and ‘relative’ contraindications of vertebroplasty – Case series of 24-osteoporotic vertebra plana with posterior/anterior wall defected neurological deficit patients treated with vertebroplasty and short segment fixation
Kakadiya (29)
The evidence base for 2017 BOAST-4 guidance on open fracture management: Are we due an update?
Jamal (7)

Do we still need anti-embolism stockings? A systematic review of their effectiveness
Awadallah (83)
17:00 to 17:30Keynote
Mechanics of joint development
Sandra Shefelbine (Northeastern)

Chairs: Andrew Phillips (Imperial) and Elise Pegg (Bath)
17:30Meeting close and awards
BORS President: Deborah Mason
Day 2 Close